Role of Bcl-2 family in lymphoid malignancies from 구 Watch Video
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Description: Dr Strasser talks to ecancertv at ASH 2013.nnImpaired apoptosis is considered one of the prerequisites for the development of most, if not all, cancers, but the mechanisms that guarantee the sustained survival of most cancer cells remain unknown.nnMembers of the Bcl-2 family are key regulators of apoptosis and include proteins essential for cell survival and those required to initiate cell death. Studies with transgenic mice have shown that over-expression of Bcl-2 or related pro-survival family
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