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Prof Maha Hussain speaks to ecancer at ESMO 2019 in Barcelona about data from the PROfound trial comparing the PARP inhibitor olaparib with new hormonal agents in advanced castration resistant prostate cancer.nnShe reports that in cohort A (patients with BRCA1, BRCA2 or ATM genes) progression free survival was over double in favour of the olaparib and in the overall population of cohort A and cohort B (alterations in other genes involved in DNA repair) there were similar trends.nnProf Hussain be
⏲ 3 min 98 sec ✓ 30-Sep-2019
Understand why, where and how PARP inhibitors work in clinical practice, and look into the future of targeting DDR. The e-learning is designed to support you in selecting the appropriate treatment strategy with PARP inhibitors in the appropriate patient population and to provide the best possible patient care.
⏲ 70 sec ✓ 25-Sep-2019
Prof Ray-Coquard speaks with ecancer about the importance of initial diagnosis and molecular analysis in management of granulosa cell type ovarian cancers.nnShe also discusses clinical trials in this indication, including an upcoming presentation at ESMO 2018 on the first randomised trial for patients on weekly paclitaxel. nnProf Ray-Coquard also discusses the use of PARP inhibitors with antiangeogenic factors to treat ovarian cancers.
⏲ 2 min 74 sec ✓ 06-Jul-2018
This HSE guidance is for medically vulnerable people who live in their own home and is in place for 2 weeks from March 27th 2020.nnWhat does cocooning mean? nnIt means measures to protect people who are over 70 years of age or those who are extremely medically vulnerable by minimising all interaction between them and others.nnWhat do we mean by extremely medically vulnerable?n1. People aged 70 years or oldernn2. Solid organ transplant recipientsnn3. People with specific cancers:nn- who are under
⏲ 5 min 91 sec ✓ 28-Mar-2020
Produced by Acme FilmworksnDirected by Michal Sochanhttp://www.acmefilmworks.com
⏲ 30 sec ✓ 11-Mar-2014
CreditsnCLIENT: PARPnAGENCY: Scholz & FriendsnPRODUCTION: Dorota SieradzkanANIMATION DIRECTOR: KubaSocha, Michal Socha, BrosFXnCREATION: Agnieszka Niska- Wojcik, BrosFXnREALIZATION: BrosFX: Directing, Concept Design, Animation, Postproduction
⏲ 30 sec ✓ 23-Jan-2013
Dr Susana Banerjee comments on data, during a press conference at the 2019 ESMO congress, from the PAOLA-1/ENGOT-ov25 trial.nnThis was a phase III randomised trial which looked at the maintenance combined targeted therapy of PARP inhibitor olaparib added to bevacizumab, in patients with and without a BRCA mutation.nnSign up to ecancer for free to receive tailored email alerts for more videos like this.necancer.org/account/register.php
⏲ 2 min 63 sec ✓ 28-Sep-2019
ERP PARP Webinar 2.10.23 from parp
⏲ 51 min 19 sec ✓ 15-Feb-2023
Prof Karim Fizazi (Institut Gustave Roussy, Paris, France), Dr Elena Castro (Spanish National Cancer Research Center, Madrid, Spain) and Prof Axel Merseburger (University Hospital Schleswig-Holstein, Lübeck, Germany) discuss the latest updates in prostate cancer from ASCO GU 2020 in San Francisco. nnProf Merseburger describes the latest data from the TITAN trial, in which the time to second progression (PFS2) result was positive, with the occurrence of no new safety signals. He also explains th
⏲ 9 min 18 sec ✓ 15-Feb-2020
Speaker:nYonghao Yu, PhDnUniversity of Texas, SouthwesternnnOur understanding of how the biology of various diseases relates to the central dogma that DNA encodes RNA, which encodes protein has been buoyed by rapid technological advances in DNA and RNA sequencing and has led to some of the first advances in personalized medicine. However, characterization of the final and arguably most actionable element of the central dogma, protein, has lagged behind. We are interested in developing mass spect
⏲ 44 min 93 sec ✓ 24-Sep-2020
Prof Michael Untch speaks to ecancer at ESMO 2019 in Barcelona about some of the trials covering PARP inhibitors for metastatic breast cancer.nnProf Untch outlines the OlympiAD and EMBRACA trials for patients with BRCA mutations, both with positive results.nnHe also touches on the BrighTNess study which involves a new PARP inhibitor, veliparib.nnSign up to ecancer for free to receive tailored email alerts for more videos like this.necancer.org/account/register.php
⏲ 1 min 78 sec ✓ 03-Oct-2019
Dr Tira Tan speaks to ecancer at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about the phase II DORA study. nnShe explains that the trial uses the PARP inhibitor olaparib alone or in combination with the PD-L1 inhibitor durvalumab to treat patients with platinum responsive advanced triple-negative breast cancer, thereby using a maintenance strategy to reduce the toxicities experienced by patients.nnDr Tan says that they are expecting some correlative work to come out of
⏲ 2 min 12 sec ✓ 03-Jun-2019
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