_parp-inhibitor-olaparib-as-treatment-for-pancreatic-cancer-patients-with-brca-gene-mutations.jpg "PARP inhibitor olaparib as treatment for pancreatic cancer patients with BRCA gene mutations from parp Video Screenshot Preview")
GalleryPlay Video:
(Note: The default playback of the video is HD VERSION. If your browser is buffering the video slowly, please play the REGULAR MP4 VERSION or Open The Video below for better experience. Thank you!)
⏲ Duration: 1 min 78 sec
✓ Published: 02-Jun-2019
✓ Published: 02-Jun-2019
Description:
Dr Hedy Kindler talks to ecancer at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about results from the POLO trial looking at the use of the PARP inhibitor olaparib as treatment for pancreatic cancer patients with BRCA gene mutationsnnShe explains that this trial is the first phase III trial showing that a targeted treatment in a biomarker selective group of pancreatic cancer patients can improve progression free survival.nnDr Kindler reports that patients who received ol
Dr Hedy Kindler talks to ecancer at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about results from the POLO trial looking at the use of the PARP inhibitor olaparib as treatment for pancreatic cancer patients with BRCA gene mutationsnnShe explains that this trial is the first phase III trial showing that a targeted treatment in a biomarker selective group of pancreatic cancer patients can improve progression free survival.nnDr Kindler reports that patients who received ol
Share with your friends:
Whatsapp | Viber | Telegram | Line | SMS
Email | Twitter | Reddit | Tumblr | Pinterest
Related Videos
_11-new-drug-updates-in-solid-tumors-parp-inhibitors-in-ovarian-cancer-immunotherapeutics-and-other-agents.webp "Edward Li, PharmD, MPH, BCOP, University of New England College of PharmacynnGet updated on the latest drug treatments for solid tumors and the clinical trial data behind their FDA approvals. And importantly, learn how to spot the common adverse side effects from these newly approved treatments and how to help patients manage them.nnThis activity is supported by independent educational grants from AstraZeneca, Merck Sharp & Dohme Corp, Novartis Pharmaceuticals Corporation, Puma Biotechnology")
⏲ 37 min 60 sec ✓ 09-Jan-2018
_mansoor-raza-mirza-md-on-reducing-toxicity-associated-with-parp-inhibitors-in-ovarian-cancer.webp "Mansoor Raza Mirza, MD, on Reducing Toxicity Associated With PARP Inhibitors in Ovarian Cancer from parp")
⏲ 1 min 12 sec ✓ 03-Jul-2019
_more-ovarian-cancer-patients-benefit-from-maintenance-combined-targeted-therapy.webp "Prof Isabella Ray-Coquard speaks to ecancer at ESMO 2019 in Barcelona about the PAOLA-1/ENGOT-ov25 Phase III trial, which showed the benefits of treating advanced ovarian cancer patients with bevacizumab and PARP inhibitor olaparib in the first-line setting. nnShe explains that this intensive regimen was given to patients both with and without a BRCA mutation. While both groups were found to have extended progression-free survival, this was more pronounced in the subgroup of patients with BRCA m")
⏲ 2 min 65 sec ✓ 28-Sep-2019
_latest-in-parp-inhibitors-and-combination-therapies-for-prostate-cancer.webp "Dr Dan George (Duke University School of Medicine, USA), Prof Noel Clarke (The Christie NHS Foundation Trust, Manchester, UK), Dr Friederike Schlurmann (Centre Hospitalier Universitaire de Brest, Brest, France) and Prof Eleni Efstathiou (Houston Methodist Cancer Center, Houston, USA) discuss the latest in PARP inhibitors and combinations for prostate cancer. nnIn this discussion they cover the TALAPRO-2, PROpel and MAGNITUDE trials. They discuss the use of non-OS endpoints and combination therap")
⏲ 13 min 43 sec ✓ 19-Feb-2023
_niacin-is-neuroprotective-in-a-fly-model-of-parkinsons-disease.webp "https://doi.org/10.1242/bio.022186nnLehmann et al.")
_part-1-dna-damage-response-and-parp-inhibition.webp "Short chapter from the Mechanism of Action of PARP inhibitors and Targeting DNA Damage Response (DDR) video")
_immunomodulatory-effects-of-parp-inhibition-in-brca1-deficient-triple-negative-breast-cancer.webp "Dr Constantia Pantelidou speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about a study which looked at the immunomodulatory effects of PARP inhibition in BRCA1-deficient triple-negative breast cancer (TNBC).nnShe reports that PARP inhibitors induce an anti-tumour immune response in BRCA1-deficient TNBC but not in BRCA1-proficient TNBC.nnDr Pantelidou explains that this T cell recruitment is mediated through activation of the STING pathway and this activation")
⏲ 1 min 67 sec ✓ 09-Apr-2019
_asco-2022-latest-in-prostate-cancer-including-parp-inhibitors.webp "Dr Neal Shore (Carolina Urologic Research Center, Myrtle Beach, USA), Prof Phil Cornford (Royal Liverpool University Hospital, Liverpool, UK), Prof Eleni Efstathiou (Houston Methodist Cancer Center, Houston, USA) and Prof Cora Sternberg (Weill Cornell Medicine, New York, USA) discuss the latest in prostate cancer, including PARP inhibitors. nnInitially, they discuss the latest trials and updates in prostate cancer including PROPEL, MAGNITUDE and the ARCHES trial.nnThey discuss the use of Lutetiu")
_11-new-drug-updates-in-solid-tumors-parp-inhibitors-in-ovarian-cancer-immunotherapeutics-and-other-agents.jpg)
_mansoor-raza-mirza-md-on-reducing-toxicity-associated-with-parp-inhibitors-in-ovarian-cancer.jpg)
_more-ovarian-cancer-patients-benefit-from-maintenance-combined-targeted-therapy.jpg)
_latest-in-parp-inhibitors-and-combination-therapies-for-prostate-cancer.jpg)
_niacin-is-neuroprotective-in-a-fly-model-of-parkinsons-disease.jpg)
_part-1-dna-damage-response-and-parp-inhibition.jpg)
_immunomodulatory-effects-of-parp-inhibition-in-brca1-deficient-triple-negative-breast-cancer.jpg)
_asco-2022-latest-in-prostate-cancer-including-parp-inhibitors.jpg)
![[+]](/images/menu.gif){kind=small}