_immunomodulatory-effects-of-parp-inhibition-in-brca1-deficient-triple-negative-breast-cancer.jpg "Immunomodulatory effects of PARP inhibition in BRCA1-deficient triple-negative breast cancer from parp Video Screenshot Preview")
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⏲ Duration: 1 min 67 sec
✓ Published: 09-Apr-2019
✓ Published: 09-Apr-2019
Description:
Dr Constantia Pantelidou speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about a study which looked at the immunomodulatory effects of PARP inhibition in BRCA1-deficient triple-negative breast cancer (TNBC).nnShe reports that PARP inhibitors induce an anti-tumour immune response in BRCA1-deficient TNBC but not in BRCA1-proficient TNBC.nnDr Pantelidou explains that this T cell recruitment is mediated through activation of the STING pathway and this activation
Dr Constantia Pantelidou speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about a study which looked at the immunomodulatory effects of PARP inhibition in BRCA1-deficient triple-negative breast cancer (TNBC).nnShe reports that PARP inhibitors induce an anti-tumour immune response in BRCA1-deficient TNBC but not in BRCA1-proficient TNBC.nnDr Pantelidou explains that this T cell recruitment is mediated through activation of the STING pathway and this activation
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